Publications

SELECTED PUBLICATIONS

Hossain, M. A., & Bungert, J. (2017). Genome Editing for Sickle Cell Disease: A Little BCL11A Goes a Long Way. Molecular Therapy, 25(3), 561-562. doi:10.1016/j.ymthe.2017.02.003 (link out)

Hossain, M. A., Shen, Y., Knudson, I., Thakur, S., Stees, J. R., Qiu, Y., . . . Bungert, J. (2016). Activation of Fetal γ-globin Gene Expression via Direct Protein Delivery of Synthetic Zinc-finger DNA-Binding Domains. Molecular Therapy – Nucleic Acids,5. doi:10.1038/mtna.2016.85 (link out)

Stees, Jared R., Mir A. Hossain, Tomoki Sunose, Yasushi Kudo, Carolina E. Pardo, Nancy H. Nabilsi, Russell P. Darst, et al. (2015). High Fractional Occupancy of a Tandem Maf Recognition Element and Its Role in Long-Range β-Globin Gene Regulation. Molecular and Cellular Biology 36 (2): 238–50. doi:10.1128/MCB.00723-15 (link out)

Fan, A. X., Papadopoulos, G. L., Hossain, M. A., Lin, I.-J., Hu, J., Tang, T. M., Kilberg, M. S., et al. (2014). Genomic and proteomic analysis of transcription factor TFII-I reveals insight into the response to cellular stress. Nucleic acids research, 42(12), 7625–41. doi:10.1093/nar/gku467 (link out)

Barrow, J. J., Li, Y., Hossain, M., Huang, S., & Bungert, J. (2014). Dissecting the function of the adult β-globin downstream promoter region using an artificial zinc finger DNA-binding domain. Nucleic acids research, 42(7), 4363–74. doi:10.1093/nar/gku107 (link out)

Deng, C., Li, Y., Liang, S., Cui, K., Salz, T., Yang, H., Tang, Z., Gallagher, P.G., Qiu, Y., Roeder, R.G., Zhao, K., Bungert, J., and S. Huang (2013) USF1 and hSET1A mediated epigenetics modifications regulate lineage differentiation and HoxB4 transcription. PLOS Genetics. 9,6, e1003524.

Papadopoulos, G.L., Karkoulia, E., Tsamardinos, I., Porcher, C., Ragoussis, J., Bungert, J., and J. Strouboulis (2013) GATA-1 genome-wide occupancy associates with distinct epigenetic profiles in mouse fetal liver erythropoiesis. Nucl. Acids Res. 41 (9), 4938-4948.

Rosenberg, M., Fan, A. X., Lin, I.-J., Liang, S. Y., & Bungert, J. (2013) Cell-cycle specific association of transcription factors and RNA polymerase II with the human β-globin gene locus. Journal of Cellular Biochemistry. doi:10.1002/jcb.24542 (link out)

Stees, J., Varn, F., Huang, S., & Strouboulis, J., and J. Bungert (2012) Recruitment of Transcription Complexes to Enhancers and the Role of Enhancer Transcription. Biology, 1(3), 778–793. doi:10.3390/biology1030778 (link out)

Barrow, J. J., Masannat, J., & Bungert, J. (2012) Neutralizing the function of a β-globin-associated cis-regulatory DNA element using an artificial zinc finger DNA-binding domain. Proceedings of the National Academy of Sciences of the United States of America, 109(44), 17948–53. doi:10.1073/pnas.1207677109 (link out)

Anantharaman, A., Lin, I.-J., Barrow, J., Liang, S. Y., Masannat, J., Strouboulis, J., Huang, S., et al. (2011) Role of helix-loop-helix proteins during differentiation of erythroid cells. Molecular and Cellular Biology, 31(7), 1332–43. doi:10.1128/MCB.01186-10 (link out)

Zhou, Z., Li, X., Deng, C., Ney, P. A., Huang, S., & Bungert, J. (2010) USF and NF-E2 cooperate to regulate the recruitment and activity of RNA polymerase II in the beta-globin gene locus. The Journal of Biological Chemistry, 285(21), 15894–905. doi:10.1074/jbc.M109.098376 (link out)

Liang, S. Y., Moghimi, B., Crusselle-Davis, V. J., Lin, I.-J., Rosenberg, M. H., Li, X., Strouboulis, J., et al. (2009) Defective erythropoiesis in transgenic mice expressing dominant-negative upstream stimulatory factor. Molecular and Cellular Biology, 29(21), 5900–10. doi:10.1128/MCB.00419-09 (link out)

Liang, S., Moghimi, B., Yang, T. P., Strouboulis, J., & Bungert, J. (2008) Locus control region mediated regulation of adult beta-globin gene expression. Journal of Cellular Biochemistry, 105(1), 9–16. doi:10.1002/jcb.21820 (link out)